Pericyte-mediated regulation of angiogenesis during ... - Nature
: Stimuli like hypoxia (low oxygen) trigger endothelial cells to break through the vessel wall. angiogenesis
: The new vessels adjust to the specific needs of the surrounding tissue. Pericyte-mediated regulation of angiogenesis during
: Pericytes and mural cells wrap around the new vessels to stabilize them and prevent leakage. The Therapeutic "Switch" angiogenesis
Medical research focuses on flipping the angiogenic "switch" depending on the condition:
: These cells migrate and organize into a tube-like structure.
The process typically follows four major steps to remodel the vasculature: