After hearing that Frankie died in a lab fire, Mac travels to MIT with , who is on mandatory medical leave with a broken arm. Their investigative instincts kick in when they notice a suspicious man at the memorial and learn that Frankie's supervisor also recently died in a mysterious car crash.
: Developing the "hurt/comfort" aspect of Jack dealing with his injury while still trying to protect Mac. "MacGyver" Compass (TV Episode 2017) - IMDb [S1E19] Compass
: To help Frankie process DNA samples while on the run, Mac creates a DIY centrifuge using common items like a bicycle wheel or salad spinner—noted as one of the best "hacks" in the series. After hearing that Frankie died in a lab
If you are looking to develop this specific plot further, common fan theories and follow-ups focus on: "MacGyver" Compass (TV Episode 2017) - IMDb :
: Frankie’s DNA research could be linked to future "Phoenix Foundation" cold case files or Mac's own family history.