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: Entities are now generally listed in order from benign to malignant within each section to better reflect their neoplastic progression and clinical aggressiveness.
: A new chapter focusing on the adverse prognostic implications of systemic cancers metastasizing to the skin. WHO Classification of Skin Tumours
: Continues to be categorized separately from traditional SCC. 3. New Sections & Provisional Entities
: "Primary cutaneous NUT (Nuclear protein in testis) carcinoma" is included as a new provisional entity. 4. Adnexal & Soft Tissue Tumours This is for informational purposes only
: This term is now used for "intermediate" lesions that exhibit borderline biological behavior but have specific molecular signatures (e.g., BAP1 inactivation or WNT pathway alterations).
The (5th Edition, 2025) is the authoritative global standard for diagnosing and categorizing cutaneous neoplasms. Also known as the "Blue Books," this edition shifts toward a more integrated, multidisciplinary approach that combines traditional histopathology with advanced molecular genetics and immunohistochemistry. Key Structural & Conceptual Changes Learn more : Entities are now generally listed
: The 5th edition (WCT5) organizes tumours into a rigid hierarchy: Site → Category → Family → Type → Subtype .